Santee Seafood Bistro

Santee Seafood Bistro A small intimate restaurant offering a variety of seafood, southern comfort food and spirits.

small intimate seafood restaurant where you can either dine-in, take-out, and/or purchase raw seafood (market is seasonal)

12/24/2025
12/11/2025

Drop in tomorrow, December 11 2025 for the Santee Holiday Crawl for a bit and beverage.

Get a Santee Seafood Bistro stamp and drop in to other local businesses for your chance to win gift cards.

03/15/2025
*We would love to have you on our team!*
02/21/2025

*We would love to have you on our team!*

*****NOW HIRING***
Passion for Food/Service Industry, Positive Energy, Teamplayer, Motivated, Great Smile. Come Join our Team..
Apply Today ! Send a message to schedule an interview or in person Santee Seafood Bistro
***Kitchen Staff, Server, and Bartender***

We are open;
Hours: Tuesday to Saturday 1130am-830pm, Sunday 1130am-4pm
** Catch the Vibe, Join our Team***
Looking forward to hearing from you🙂
Santee Seafood Bistro followers - Please share with someone who you would love to see as apart of our Team.

Joiin us this Friday & Saturday 4pm-6pmPRE- SUPER BOWL Santee Seafood Bistro OYSTERS on the  1/2 HALF ShellBUFFALO  SHRI...
02/05/2025

Joiin us this Friday & Saturday 4pm-6pm
PRE- SUPER BOWL Santee Seafood Bistro
OYSTERS on the 1/2 HALF Shell
BUFFALO SHRIMP
WINGS and much much more..featuring "Bobby Zee" Robert Bobby Zee Zangara
Please share

Thursdsy-January 23, 2025
01/23/2025

Thursdsy-January 23, 2025

Address

648 Bass Drive
Santee, SC
29142

Opening Hours

Tuesday 11:30am - 8:30pm
Wednesday 11:30am - 8:30pm
Thursday 11:30am - 8:30pm
Friday 11:30am - 8:30pm
Saturday 11:30am - 8:30pm
Sunday 11:30am - 4pm

Telephone

+18038544840

Website

Alerts

Be the first to know and let us send you an email when Santee Seafood Bistro posts news and promotions. Your email address will not be used for any other purpose, and you can unsubscribe at any time.

Share