M Brothers at Mayo

Name: M Brothers at Mayo
Address: 14335 Hospital Drive Suite 100, Jacksonville, FL, 32224, US
Telephone: +19049530409

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M Brothers at Mayo

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Open to the public. A Medure Brothers Culinary Concept.

A hidden gem in the Mayo Clinic Jacksonville Atrium, M Brothers offers seasonal, globally inspired cuisine, craft cocktails and warm hospitality in a full-service dining experience.

10/09/2026

Thanksgiving is right around the corner, and we’d love to make things a little easier this year! 🍂

Let our chefs handle the cooking with our chef-prepared Thanksgiving To Go packages, featuring a full holiday meal that’s ready to heat and serve at home. We’ll even include reheating instructions so you can spend less time in the kitchen and more time around the table.

📅 Curbside pickup at M Brothers at Mayo on November 24 & 25.

Make Thanksgiving easier this year and reserve your meal today!

🦃 Order online: https://order.toasttab.com/online/m-brothers-at-mayo-4500-san-pablo-rd-s

10/07/2026

Our 2026 Culinary Passport series wraps-up Saturday, October 17, with a one-night-only journey to Lebanon.

Join us for a four-course tasting inspired by Lebanon’s rich culinary traditions, Mediterranean coastline, and abundant agricultural regions. Expect fresh herbs, grains, vegetables, legumes, seafood, and aromatic spices, thoughtfully reimagined through a refined culinary lens.

$90 per person
$135 with curated w**e pairings

One night. Four courses. A journey to Lebanon.

Reserve your table and join us for the next stop on the Culinary Passport.
https://www.opentable.com/booking/experiences-availability?rid=1215757&restref=1215757&experienceId=793477&utm_source=external&utm_medium=referral&utm_campaign=shared

10/05/2026

A closer look at M Brothers. ✨

A space designed for thoughtful food, warm hospitality, and gathering around the table.

We’re proud to serve the Mayo community and welcome guests from near and far to M Brothers at Mayo.

Come settle in, stay awhile, and let us take care of the rest.

09/22/2026

CULINARY PASSPORT MENU REVEAL 🌍

Our next Culinary Passport dinner is this Saturday, September 26, as we travel to Marseille for an evening inspired by the flavors and traditions of the region.

Swipe to see the full four-course menu, crafted by Chef Thomas Rivers with w**e pairings selected to complement each course.

Reservations filled quickly for this one, so if you’ve been meaning to join us, check OpenTable for any remaining availability.

Can’t make this one? Our final stop of the year is Lebanon on October 17. Reservations are available now through OpenTable.

09/07/2026

We’ll be taking the day off today Monday, September 7 for Labor Day.

We’ll be back open for regular service hours tomorrow, Tuesday, September 8.

Happy Hour: Monday - Friday in the Lounge 4:00 PM – 6:00 PM
Lunch: Monday – Friday | 11:00 AM – 2:00 PM
Dinner: Monday – Saturday | 5:00 PM – 9:00 PM
Closed Sundays

See you then! 💙

09/01/2026

Culinary Passport is our signature dinner series at M Brothers, inviting you to explore the flavors, traditions, and stories of a different destination each month.

✈️ Next Stop: Marseille
Saturday, September 26
Book your seat: https://www.opentable.com/booking/experiences-availability?rid=1215757&restref=1215757&experienceId=793473&utm_source=external&utm_medium=referral&utm_campaign=shared

🇱🇧 Then, Lebanon
Saturday, October 17
Book your seat: https://www.opentable.com/booking/experiences-availability?rid=1215757&restref=1215757&experienceId=793477&utm_source=external&utm_medium=referral&utm_campaign=shared

Optional w**e pairings are available for both evenings. Seats are limited — reserve your spot and join us for the journey.

08/18/2026

Our next Culinary Passport Dinner is this Saturday, August 22, and we’re officially fully booked! 🌎🍴

For our guests who have already secured their seats, here’s a look at the four-course menu awaiting you as we explore the flavors of Venezuela.

FIRST COURSE
Ceviche
Red Snapper, Shrimp, Charred Citrus, Tostones, Avocado, Red Onion, Red Bell Pepper, Cilantro Oil
Paired with Aveleda Alvarinho

SECOND COURSE
Arepa Trio
Lobster Reina Pepiada — Blue Corn, Avocado, Finger Lime, Pickled Shallot
Pork Belly Pabellón Criollo — Yellow Corn, Black Beans, Puffed Rice, Sweet Plantain Jam, Cotija Cheese
Oyster Mushroom — Red Corn, Leeks, Piquillo Peppers, Roasted Corn, Queso Asadero, Salsa de Ajo
Paired with Château des Jacques Clos des Jacques Chardonnay

THIRD COURSE
Asado Negro
48-Hour Braised Wagyu Beef Cheek, Long-Grain Rice, Caramelized Plantain Soubise, Carrot, Cashew Crumble
Paired with Château Chapelle d’Aliénor Bordeaux

FOURTH COURSE
Bienmesabe
Sponge Cake, Rum, Meringue, Coconut Custard Mousse, Passionfruit, Cinnamon Tuile
Paired with Villa Rosa Moscato d’Asti

We can’t wait to welcome everyone this Saturday for an evening of Venezuelan flavors, thoughtful w**e pairings and culinary discovery. 🇻🇪✨

These dinners fill up quickly, and we’re working on the next Culinary Passport regions and dates now. We’ll share what’s next as soon as the details are ready!

08/05/2026

Still thinking about our last Culinary Passport Dinner? So are we. 🌎✨

As we look back on the incredible flavors and memories from our Madagascar experience, we're already packing our bags for the next destination...

🇻🇪 Venezuela | Saturday, August 22

Join us for another unforgettable evening featuring a thoughtfully crafted multi-course menu inspired by the rich culinary traditions of Venezuela. From bold flavors to beautifully plated courses, every Culinary Passport Dinner offers a unique opportunity to experience the world—one destination at a time.

🍽️ Our full menu reveal is coming soon.

Reservations are now available, and seating is limited. Reserve your seat and continue the journey with us.
https://www.opentable.com/booking/experiences-availability?rid=1215757&restref=1215757&experienceId=736566&utm_source=external&utm_medium=referral&utm_campaign=shared

07/21/2026

Join us this Saturday, July 25 at M Brothers as our Culinary Passport Dinner transports you to the island of Madagascar. Experience a thoughtfully crafted multi-course menu inspired by the country's rich culinary heritage, where African, Asian, Indian, and French influences come together through vibrant spices, fresh ingredients, and unforgettable flavors.

From savory specialties to a decadent finale, this is a one-night-only dining experience you won't want to miss.

🍽️ Saturday, July 25
📍 M Brothers at Mayo
🎟️ Seating is limited—reserve your table today: https://www.opentable.com/booking/experiences-availability?rid=1215757&restref=1215757&experienceId=736561&utm_source=external&utm_medium=referral&utm_campaign=shared

06/04/2026

A look back at our Culinary Passport journey to Greece 🇬🇷✨

Vibrant Mediterranean flavors and thoughtfully paired w**es, May's dinner transported guests to the sun-soaked shores of Greece for one unforgettable evening.

Thank you to everyone who joined us! Each Culinary Passport dinner is a celebration of culture, cuisine, and connection, and we're grateful to share these experiences with you.

Next stop: Sicily on June 27. 🌎🍷

Address

14335 Hospital Drive Suite 100
Jacksonville, FL
32224

Telephone

+19049530409

Website

http://mbrothersatmayo.com/

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